Polynucleotides
Unlocking Radiant Skin.
composed of nucleotide monomers. They are essentially long chains of nucleotides, which are the building blocks of DNA and RNA. These molecules have various roles in the body, including cellular repair and regeneration. In treatments, polynucleotides are used for their regenerative properties, helping to improve skin quality by promoting cell turnover and healing.
This treatment helps to stimulate natural regenerative processes, leading to improved skin texture, elasticity, and hydration.
It is also great for people who want to prevent the signs of ageing on the skin.
What are Polynucleotides?
Polynucleotides are long chains of nucleotides, which are the building blocks of DNA and RNA. These molecules are derived from salmon DNA, which has been found to be highly biocompatible with human tissue.
The treatment works at a cellular level to stimulate tissue repair, promote collagen production, and improve overall skin quality.
Key benefits of Polynucleotides
Polynucleotides offer numerous advantages for skin health and appearance:
Improved skin texture and tone
in fine lines and wrinkles
Enhanced skin firmness and elasticity
Brighter, more radiant complexion
Reduction in pigmentation and dark circles ( around the eyes)
of scars and stretch marks
Overall skin rejuvenation
Polynucleotides Packages:
Per area: £350
Per area: £600
Per area: £850
FAQs
Which areas can be treated with polynucleotides?
At Karwal Aesthetics, we offer Plinest polynucleotides for various areas of the face and body:
Face: Mid-face and lower face
Eyes: Under-eye area, crow’s feet, upper eyelids
Neck and décolletage: For addressing crepey skin and horizontal lines
Hands: To improve skin quality and reduce signs of ageing
How many polynucleotide sessions are needed?
The number of treatments required varies depending on individual concerns and goals:
Initial course: Typically 2-4 sessions spaced 2-4 weeks apart
Maintenance: Follow-up treatments every 6 months to results
Severe concerns: May require more intensive treatment protocols
When will I see results from polynucleotides?
Results from Plinest Polynucleotide Treatment treatments develop gradually:
Immediate: Some hydration and subtle glow may be visible straight away
2-4 weeks: Noticeable improvements in skin texture and tone
4-8 weeks: More significant improvements as collagen production increases
3-6 months: Optimal results become apparent
Results typically last 6-12 months, depending on individual factors such as age, lifestyle, and skin condition.
Who is suitable for polynucleotides treatment?
Polynucleotides are suitable for most adults looking to improve their skin quality. Ideal candidates include those who:
Have early to moderate signs of ageing
Want natural-looking rejuvenation without fillers
Have sun-damaged or dehydrated skin
Are looking for preventative anti-ageing treatments
Have realistic expectations about results
Where do we offer polynucleotides?
We offer polynucleotide treatments at our clinic in London Mayfair. Our practice is conveniently located in the heart of Mayfair, one of London’s most prestigious areas, making it easily accessible for across the capital.
Clinic Location
Address: 15 Dover Street, London, W1S 4LP
Our Mayfair clinic provides a and discreet environment where you can receive your Plinest treatments from Dr Arun, an experienced aesthetic practitioner. The clinic is equipped with modern facilities and to the highest standards of safety and .
How to Find Us
By Underground: Green Park station (Jubilee, Piccadilly, and Victoria lines) is just a short walk away
By Bus: bus routes serve the Mayfair area
By Car: Limited street parking available; several car parks nearby
To book your polynucleotides consultation or treatment, .
Benefits of Plinest Eyes Polynucleotides
Improved Skin Texture: The treatment helps to smooth out fine lines and wrinkles, giving the skin a more refined texture.
Enhanced Elasticity: By boosting collagen production, Plinest Eyes improves skin elasticity, making it more resilient and firm.
Increased Hydration: The help to maintain moisture levels in the skin, preventing dryness and dullness.
Natural-Looking Results: The regenerative properties of polynucleotides provide a subtle and natural enhancement, avoiding the overly artificial look that some treatments can produce.
Minimal Downtime: Plinest Eyes is a minimally invasive procedure with little to no downtime, allowing individuals to resume their daily activities shortly after treatment.
What is the aftercare with ?
Aftercare Notes for Sunekos, Profhilo & Plinest:
Needle entry points, redness, bruising, and asymmetry around injection sites immediately after treatment is normal due to the very nature of the treatment.
There may also be some tenderness as the and inflammation sets in. These symptoms will resolve over the next 2-7 days, depending on your individual response to the .
For 24 hours avoid:
Touching your face
Applying makeup
Skincare with active ingredients
No alcohol
No exercise
No hot showers or sauna/steam rooms
Both Plinest and Sunekos are treatments, but they differ in their composition and mechanisms of action. Sunekos contains a patented formula of hyaluronic acid combined with a specific blend of amino acids, whilst Plinest uses polynucleotides derived from salmon DNA.
Key differences include:
Active ingredients: Sunekos relies on hyaluronic acid and amino acids to stimulate the extracellular matrix, whereas Plinest uses polynucleotides for cellular regeneration and tissue repair.
Mechanism: Sunekos works by providing the building blocks for collagen and elastin synthesis, whilst actively stimulates activity and has additional anti-inflammatory and antioxidant .
Treatment areas: Both can be used on similar areas, though Plinest Eye is specifically formulated for the periorbital region, whilst Sunekos has different formulations (Sunekos 200 and Sunekos 1200) for varying levels of skin laxity.
Results: Both provide natural-looking improvements. However, Sunekos is the preferred product at Karwal Aesthetics, delivering more dramatic results and better improvement in hyperpigmentation, fine lines, and skin texture—especially crepey skin.
Both and Profhilo are bio-remodelling treatments that stimulate skin rejuvenation, but they differ in their composition and approach:
Active ingredients: Profhilo contains highly concentrated hyaluronic acid (HA), whilst Plinest uses polynucleotides derived from salmon DNA.
Mechanism of action: Profhilo works through bio-remodelling with HA to stimulate collagen and elastin production in four different types of collagen. Plinest works by directly stimulating fibroblast activity and has additional anti-inflammatory and antioxidant properties.
Injection technique: Profhilo typically uses the BAP (Bio Aesthetic Points) technique with 5 injection points per side of the face, whilst Plinest requires multiple injection points distributed across the treatment area.
Spread: Profhilo’s unique formulation allows it to spread more easily under the skin after injection, whilst Plinest remains more localised to the injection sites.
Hydration vs. regeneration: Profhilo primarily focuses on intense hydration and bio-remodelling, whilst Plinest cellular regeneration, tissue repair, and anti-inflammatory effects.
Treatment areas: Both can be used on similar areas, though Profhilo is particularly noted for its lifting and hydrating on the face and neck, whilst Plinest offers targeted formulations like Plinest Eye for specific concerns.
Results: Both provide improvements. However, Profhilo is the preferred product at Karwal Aesthetics between the two. Profhilo delivers a natural glow, plumpness, and hydration to the skin.
Potential side
Plinest polynucleotide treatments are generally well-tolerated, but some temporary side effects may occur:
Mild swelling at injection sites
Slight bruising (more common in sensitive areas)
Redness or tenderness
Small bumps at injection points
These effects typically resolve within hours. Serious side effects are rare when performed by qualified practitioners.
Business Enquiries
Mayfair, London2nd Floor, 15 Dover Street, W1S 4LP
Closed
10: :00
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10: :00
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0% finance is available on all treatments from £500. Find out more by visiting our Payment Plan page.
Please note: our clinic is on the second floor with stair access only.